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GO TO THE SYNTHETIC AESTHETICS WEBSITE FOR MORE INFORMATION

How would you design nature?

Synthetic Biology is a new approach to engineering biology, generally defined as the application of engineering principles – such as standardization and modularity – to the complexity of biology. The aim is to ‘make biology easier to engineer’, through the design and construction of new biological parts, devices, and systems, and the re-design of existing biological systems for useful purposes, from biofuels to new medical applications. Biology is becoming a new material for engineering – a new technology for design and construction.


What is Synthetic Biology?

Synthetic biology involves understanding and modelling natural entities and processes at the molecular scale; modifying existing organisms such as bacteria through intentional design and construction; building synthetic organisms capable of accomplishing specified goals; and constructing new organisms from the bottom up.

Its supporters hope to make biology something that can be designed and constructed in the same way electronic components are pieced together to produce working computers. By using standard biological parts – ‘biological bricks’ made of DNA – some synthetic biologists hope to simplify the making of useful organisms. Other scientists are attempting to design entirely new living systems – protocells – constructed from different biochemistry.

Design is central to synthetic biology, as the living world becomes a product of design and manufacturing choices, rather than evolutionary pressures alone. But designing nature is not straightforward. We tend to understand design in terms of tangible objects like telephones and buildings than in the realm of microscopic biology. It becomes much more complicated when the realm of design is living material.

What does it mean to design nature, and how do designers fit into the process of making machines from biology? Architects work with structural engineers, product designers work with mechanical engineers. Could synthetic biology – and the questions it raises about the synthetic construction of life – benefit from such interactions?

What is Synthetic Aesthetics?

Synthetic Aesthetics is a research project run by the University of Edinburgh, Scotland, and Stanford University, California. Synthetic biologists, like many engineers, are concerned with ‘design’. By instigating new collaborations between synthetic biologists, designers, artists, and social scientists, we are exploring the shared territory between synthetic biology and creative practice.

Can these collaborations inform and shape the developing field of synthetic biology? What insights can design offer in designing microscopic entities for a human-scale world? Can the exchange of skills and ideas enable the development of new forms of craft and collaboration? What can art and design learn from synthetic biology?

Synthetic Aesthetics is bringing together six synthetic biologists and six artists and designers to help with the work of designing, understanding and building the living world. From July to December 2010, our twelve residents will embedded residencies. Each pair spend two weeks in the bioengineering laboratory and two weeks in their exchange partner’s art or design workspace.

The residents will share their practice, knowledge and skills, and develop new project ideas together. These are balanced exchanges, where both disciplines inform the other. We aim to catalyze interactions, develop transferable knowledge and skills, and establish a continuing network of collaborations.

Art and design engagement can encourage thought and debate in unique and innovative ways – we hope collaborative investigation beyond representation and visualisation will emerge, exploring new ideas in the processes of synthetic biology and design. Synthetic Aesthetics social scientists, Pablo Schyfter and Jane Calvert, and designer/artist Alexandra Daisy Ginsberg will be supporting, documenting and studying the exchanges.

We seek more than one-off experiences: the interactions will contribute to ongoing work in both communities, developing new spaces for practice, cooperation, and debate. Long-term interaction could enable design concerns to be reflected better in synthetic biology, enabling inclusive and responsive technology development.

We aim to construct the groundwork that could inform new schools of engineering and research, new schools of art and design, innovative approaches to the study of synthetic biology in society, and new approaches to societal engagement with synthetic biology.

We hope each pair will develop a collaborative project beyond the four-week intensive exchange. These projects will differ between the six pairs, perhaps physical objects, writing, film,protocols, a bacteria or something else will emerge. Our residents come from all over the world and adopt different approaches to synthetic biology (including protocell, ‘BioBrick’, and plant science); and to art and design (including architecture, bioart, industrial design, smell, music).

Synthetic Aesthetics will endeavour to provide support for ongoing collaborations. In 2011, we aim to organize two workshops, one for the synthetic biology community and one for artists and designers. We will publish the output of the residencies, framed by the issues raised by synthetic biology – scientific, ethical, sociological, design and artistic.

Synthetic Aesthetics is jointly funded by the National Science Foundation (USA) and the Engineering and Physical Sciences Research Council (UK). The Synthetic Aesthetics project team comprises Drew Endy (Stanford, bioengineering), Alistair Elfick (Edinburgh, bioengineering), Jane Calvert (Edinburgh, social science), Pablo Schyfter (Stanford/Edinburgh, social science) and Alexandra Daisy Ginsberg (Stanford/Edinburgh, art/design).

Participating

The call for participants for the twelve residencies is closed, but if you are interested in joining our network as an artist/designer or scientist/engineer, please get in touch. This website will feature the ongoing results of our work and track the collaborations we establish.

Al images and text from Synthetic Aesthetics.

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Mikael Metthey is a French designer interested in exploring new ways of combining science and design.
He uses design to explore and debate the future implications of emerging technologies. With his designs, he aims to raise new questions about the way technology impacts on people’s lives and how it can be used in unconventional but beneficial ways.
He believes in the social potential of emerging medical technologies. He has a special interest for biological organisms’ abilities and the ways in which they can be manipulated to create new functionalities.
Mikael completed an MA in Design Interactions at the Royal College of Art in 2007 He is currently working for Samsung Design Europe as an interaction designer.

The Pathogen Hunter

Throughout our evolutionary process, we always lived in a symbiotic tacit agreement with infectious organisms. There are approximately ten times more bacteria in the human body than there are human cells and about half of our DNA is made of virus-like components.
These organisms perform some of the most important roles in maintaining life on this planet. And yet, changes in that balance cause viruses and bacteria to be responsible for some of the deadliest diseases.
The technological improvements on the detection of infectious organisms are opening doors to future disease surveillance schemes designed to monitor and forecast potential epidemics, therefore keeping low levels of infection among the population.
Are these tools contributing to global wellbeing or excessive paranoia? Are we promoting a health-educated society or conceiving geographical hypochondria?
Rapid detection of infectious organisms will change individuals and society’s perceptions on health. We are interested in exploring the richness of behaviours and etiquette that will emerge from the collision of multi disciplinary perspectives.
Rather than focusing on the impact of such technologies at the epicentre of healthcare, we are interested in exploring the consequences of the shockwaves, therefore expanding the project to a wider spectrum.
From the research perspective:  The collaboration has given the AptaMEMS-ID project consortium the opportunity to disseminate cutting edge research concepts in microbiology and engineering to the wider publics in a format that is very different from the usual academic routes. This is providing us with new and difficult challenges, well outside of our traditional comfort zone.
Designers:
Susana Soares Mikael Metthey
Scientists:
Prof Calum McNeil, Newcastle University Prof Colin Harwood, Newcastle University

PoxTeddy

In an utopian future, we can imagine that when a deadly virus is contollable, it becomes trivialised and de-mystified to act as a recreational commodity. We would relate to it with stories, we would give them identities, we would familiarise ourselves with their history.

Today, chickenpox parties are frequently organised to synchronise children’s exposure to the disease. Poxteddy is a medical product designed for parents to control the transmission of the varicella virus (chickenpox).

Chickenpox is an interesting example because it holds a strong division of opinions when it comes to children’s vaccination. Some parents feel that natural immunity could be more effective than a medical vaccine.

In this perspective, Is it ethically correct to facilitate contagious behaviours or develop toys and spaces purposefully infecting children with chickenpox to build up their immunity? How would we change our reactions towards viruses if they became integrant to our lives?

The focus of my work is the communication of the evolving sense of control we have over microscopic organisms, such as viruses. Looking into children’s apprehension of the needle, I am searching for more intimate ways to approach the process of vaccination. Then, offering an alternative way of immunising children. I aim to use design to stimulate debates and questions on the role of technology in future medical issues; by provoking a collision between the strange and the familiar.

Meat Stick

Scientists are developing methods of growing meat in labs using animal cells. This area of research, called In-Vitro Cultured Meat Production, raises all sorts of complex issues about the meaning of food.

The future of our alimentation can be a rather obscure issue. Many questions arise from the present uncertainties of meat production. The role of the food supplier is changing as the industry evolves.

The relationship between fear and trust of food fuels the debate about the ethical implications of replicated foods.

The outcome of the project is a portable identification pen, which scans the meat to let the consumer know about its provenance. The pen uses Near-infrared spectroscopy (NIRS), which is a spectroscopic method that uses the near-infrared region of the electromagnetic spectrum. Typical applications include pharmaceutical, medical diagnostics, food and agrochemical quality control. The technology is used to deduce the origin of the meat depending on its chemical components, thus allowing the consumer to be less apprehensive.

The ways of using the pen depend on the concerns of the consumers. For example, if the consumers have no concerns to start with, will the creation of this object trigger an instant paranoia about the origin of the food? To what level of precision should we know where our meat is coming from?

To see more of Mikael Metthey go to his website.

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Tuur Van Balen (Belgium, 1981) is a designer and researcher eager to push the boundaries and methodologies of design in order to explore the rich interaction between people and technology. He has a special interest in invisible cities, synthetic biology and the ‘Metro weird-feed’.

He holds an MA degree in Design Interactions from the Royal College of Art and works as a freelance designer and researcher in service design, interaction design and design strategy. Tuur also initiates his own design research projects, often collaborating with scientists, from synthetic biologists to sociologists.

Keen to experiment with different places for design, Tuur has worked with London based thinktank Demos, organised a guerilla-exhibition at a biotech-conference, presented several times at the Institute for Advanced Studies in Lancaster and performed an on-stage yoghurt DNA-hack in front of 400 people. Currently, he collaborates with the Centre for Synthetic Biology and Innovation at Imperial College.

Before moving to London, Tuur graduated a MSc degree in Industrial Design Engineering at the Delft University of Technology and worked at several design agencies in the Netherlands.

Pigeon D’Or (In Progress)

This project explores how pigeons can serve as a (open source) platform and interface for synthetic biology in an urban environment. By modifying the metabolism of pigeons, and specifically the bacteria that live in their gut, synthetic biology might allow us to add new functionality to what is by many seen as flying rats. This would happen through feeding the pigeons special bacteria and would be as harmless to them as eating yoghurt is to us.
The first part of this project consists of a contraption that would allow these pigeons to become part of your house, part of the architecture. This pigeon house is attached to your windowsill and allows you to feed the pigeons, separate and select them and direct them through different exits.
Further on, the project will proceed investigations into pigeon-metabolisms and attempt to create bacteria that would allow a pigeon to defecate biological soap.

The technology is based on last year’s iGEM (International Genetically Engineered Machine competition) project at Imperial College London. The team of undergraduate students came up with an method of delivering medicines to the human gut (getting it past the acidity of the stomach) using bacteria for protein production and delivery. When refined, this technology might have incredible advantages over today’s medication. However, I was interested in exploring the potential implications of modifying such metabolisms on a larger scale.
The city is such a larger scale. I like to think of a city as this vast and incredibly complex metabolism of which the human species is the tiniest of fractions: tiny yet intensely linked into an intricate organic embroidery beyond our understanding. It is in this hugely complex fabric that (future) biotechnologies will end up.

And to me, feral pigeons present themselves as the ideal platform and interface for urban biotechnology. While seen by many as venom, one could argue they’re actually a product of biotechnology as their ancestors were designed to deliver post, spy during the war, race, tumble of just look pretty. He might not have phrased it that way, but that is one of the reasons Charles Darwin became a pigeon fancier. Mostly though, it is the rich culture around pigeon racing that was so inspiring for this project: from the refined pigeon-psychology to the social and economical practices.

Synthetic Immune System

Synthetic Biology’s potential to make healthcare more personal and participatory might turn us into our own doctors and pharmacists; constantly monitoring and tweaking our body. It might even allow to externalise our immune system by outsourcing metabolic processes to external micro-organisms. These micro-organisms, for instance yeasts, sense and diagnose anomalies in our body to produce and deliver chemicals accordingly. Such a Synthetic Immune System would be tailored to one’s genetic predisposition, age, lifestyle and therefore risk.
This synthetic immune system is a network of biosensors, made of yeast. Each vessel contains a different yeast, designed to monitor a specific anomaly for a specific person; helping break down lactose, caffeine or other ingredients, detecting vitamin deficits or diseases and producing chemicals or drugs accordingly. The selection of biosensors is personal and relies on one’s genetic predisposition, lifestyle and fears.
The yeasts are fed with water and sugar from the central bowl. When using the spoon to stir the mixture, a drop of blood drips into the system to disclose your body’s state. Your synthetic immune system will need feeding every evening to produce for your needs overnight. Every morning, use the mouthpiece to take in the different remedies produced specifically for today.
This project is developed as part of EPSRC’s Impact! Exhibition at the Royal College of Art in collaboration with the Centre for Synthetic Biology and Innovation at Imperial College.

London Biotopes

Only a small amount of the pharmaceuticals and chemicals we swallow are taken up in our bloodstream, most of them pass through our bodies into the city’s wastewater. Since wastewater treatment plants are not designed to remove pharmaceuticals, the contents of our medicine cabinets eventually end up in the drinking water. This results in local differences in tap water, based on the food we eat and the drugs we take.
I branded tap water from three different areas: Notting Hill tapwater benefits from the highest density of organic shops, tapwater in the city of London is enhanced with various stimulants and Golders Green ‘produces’ a very fertile water due to the low concentration of people taking anti-conception pills.
This branded tap water was then sold on a sunny Saturday morning on Broadway market and people were asked to also put their tap water on the map, speculating it’s special qualities. On the project website, people also added stories about their tap water to the map. The result is a new map of London, revealing potential local city-body ecologies or biotopes.
This is part of the ‘My City = My Body’ project, a design research project on how the rise of bio-technologies might influence our future interaction with the city. In this part, I created a series of public interventions to critically engage the audience in a future scenario, balancing fiction and reality.

For more of Tuur van Balen go to his website.

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DOWNLOAD DE ‘ORNAMISM THESIS’ HIER.

81 pagina’s

Heeft u liever een gedrukte versie te leen? Neem dan contact met mij op via info@ornamism.com ik zal dan een gedrukte versie kosteloos opsturen.

“Hoe past BioArt kunsthistorisch in het geheel? Hoe is BioArt ontstaan? Wat heeft BioArt te bieden aan de mens? Wat zijn de toekomstplannen van deze stroming? Dit zijn vragen die ik beantwoord door de visies en theorieën van menig biokunstenaar, geesteswetenschapper, biowetenschapper en filosoof te bestuderen. Door deze stroming te hebben onderzocht kan ik concluderen welke rol (mijn) fotografie kan innemen in dit geheel.”

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“Always wanted to be at the forefront of riveting art that is trans-disciplinary and pushes the boundaries of technological and artistic possibilities? Then submit your application for the Designers and Artists 4 Genomics Award and take a chance on winning a euro 25.000,- project!

The Designers & Artists 4 Genomics Award highlights and explores the exciting and novel possibilities between design, artistic practice and Life Sciences. Inaugurated by the Netherlands Genomics Initiative, the Centre for Society and Genomics, and Waag Society, the Designers & Artists 4 Genomics Award aims to stimulate emerging designers and artists to delve into the world of bio-art, and produce new work together with the Netherlands most prestigious genomics centres, for example in the field of sustainability, food, health, bio-informatics, agriculture, and safety.

Graduated no longer than five years ago? Fascinated by the breakthroughs of Life Sciences, and with a knack for applied arts and/or design? Then we want you to send in your CV, portfolio, and idea for a project that combines artistic merit with the vast developments in genomics research.

What do we offer?
After a closed-door pre-selection 20 artists/designers will be invited to pitch their idea and meet the Genomics Centres at a speed date. Following the latter, the Genomics Centres and artists/designers decide if there’s a mutual match to develop the idea for the Award further.
These sessions are scheduled on September 24th 2010 during PICNIC10 in Amsterdam.
In case of a match, the teams of artist/designer and scientist develop the project idea further towards a proposal for the Award. The 3 winning proposals, selected by an expert jury, are allotted each euro 25.000,-, and are exhibited in their realised form at Naturalis in Leiden, mid 2011.

Designers&Artists 4 Genomics Award is an initiative of The Netherlands Genomics Initiative [http://www.genomics.nl/], the Centre for Society and Genomics [http:www.society-genomics.nl] and Waag Society [www.waag.org].

The Netherlands Genomics Initiative (NGI) aims to ensure that society and economy benefit from the breakthroughs enabled by genomics in the fields of health, agro-food, sustainability, enabling technologies and society.

The Centre for Society and Genomics (CSG) studies and improves the relationship between genomics and society. CSG engages society by means of social research, interaction, dialogue and education. It strives to develop novel and effective methods of communicating scientific issues to the public as well as improving existing forms of communication and education about life sciences.

Waag Society develops creative technology for social innovation. The foundation researches, develops concepts, pilots and prototypes and acts as an intermediate between the arts, science and the media.

The participating genomics centres are:
Cancer Genomics Centre
[http://www.cancergenomics.nl/]
Celiac Disease Consortium [http://www.celiac-disease-consortium.nl/]
Centre for Medical Systems Biology [http://www.cmsb.nl/]
Netherlands Consortium for Healthy Ageing [http://www.healthy-ageing.nl/]
VIRGO Consortium [http://www.virgo.nl/]
Centre for BioSystems Genomics [http://www.cbsg.nl/]
Nutrigenomics Consortium [http://www.nutrigenomicsconsortium.nl/]
Ecogenomics Consortium [http://www.ecogenomics.nl/]
Kluyver Centre for Genomics of Industrial Fermentation [http://www.kluyvercentre.nl/]
Netherlands Bioinformatics Centre [http://www.nbic.nl/]
Netherlands Consortium for Systems Biology
Netherlands Metabolomics Centre [http://www.metabolomicscentre.nl/]
Netherlands Proteomics Centre [http://www.netherlandsproteomicscentre.nl/]
Forensic Genomics Consortium Netherlands [http://www.forensicgenomics.nl/]
Netherlands Toxicogenomics Centre [http://www.toxicogenomics.nl/]“

Source: Designers & Artists 4 Genomics Award Facebook

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GOGBOT 2010, Wanna Shock your Senses?

More than 250 artists, performers, musicians and other creative spirits will show their talents at 10 locations of the free entrance expo’s. Four days you can be part of this art music and technology spectacle. Interactive installations, insect-robot-build-workshops, electric fish, bio-installations, nano-technology, film, Japanese bacteria machines, artificial intelligences, cyborgs, magnetic fields, Beauty Parlour of the Future, Revenge of the Killer-iPhone, The bad days of Britney-Spears and of course an extended music program!

The Singularity is Near – Resistance is Futile

GOGBOT 2010 deals with the controversial concept of the Technological Singularity, about the exponential growth of technology today leading to an explosion of Artificial Intelligence within a few decades, declaring man to become the pet of computers, where in the end AI will be ruling the universe….

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artists:

CREW
DAAN ROOSEGAARDE
NATASHA VITA-MORE
CARSTEN NICOLAI
ANGELO VERMEULEN
HESTER SCHEURWATER
ADRI SCHOKKER
SONJA-VANESSA SCHMITZ
DAVID SCHEIDLER
SAYGIN SOHER
FREDERIK DE WILDE ism LAB[au]
ADAM BRANDEJS
HERMEN MAAT + KAREN LANCEL
VIA ORAL
HIDEKI KANNO
NEVERPORN COMMUNITY
BROERSEN & LUKACS
JODI
PAUL KLOTZ
DANJA VASILIEV
ARNO COENEN
JULIKA RUDELIUS
ANKE ECKARDT
JAAP MUTTER
MARTIJN VERHALLEN
HIDEYUKI ANDO, TOMOFUMI YOSHIDA, TARO MAEDA, JUNJI WATANABE
PIXELPORN

VIRTUAL WORLDS SINGULARITY CONTEST
YOUNGBLOOD AWARD 2010 19 best of graduates from 10 Dutch bachelor art academies
TENT ACADEMY AWARD
WORMSHOP

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Workshops:

GIJS GIESKES & KARL KLOMP
CHRISTIAN ZOLLNER & VICTOR MAZON

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Lectures:

NATASHA VITA-MORE (Keynotespeaker transhumanism)
ARJEN KAMPHUIS (Futurist)
prof. DAVE BLANK (mr. Nanotech)
KOERT VAN MENSVOORT (Next nature)
ERIC JORIS (Crew)

\\

Music:

ETIENNE DE CRECY
ALVA NOTO
BENGA
EPROM
YMCK
ATOM TM
SICKBOY
LADYSCRAPER
BROKEN NOTE
LOOPS HAUNT
TEAM PLASTIQUE
BRUTUZZ VS GOMES
DION 47
030303
DIGITAL SCARAMOUSH
DORIAN CONCEPT
MAZE
UNYX
ACTODI
CAVEMEN
JEAN PLASTIQ

GO TO THE GOGBOT WEBSITE FOR MORE INFO!

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Taryn Simon was born in New York in 1975. Her most recent work, An American Index of the Hidden and Unfamiliar, reveals that which is integral to America’s foundation, mythology and daily functioning, but remains inaccessible or unknown to a public audience.
Her earlier work, The Innocents, documents cases of wrongful conviction in the United States and investigates photography’s role in that process. Simon’s photographs have been exhibited nationally and internationally, including solo shows at: Whitney Museum of American Art, New York; Museum Fur Moderne Kunst, Frankfurt; P.S.1 Contemporary Art Center, New York; High Museum of Art, Atlanta; and Kunst-Werke Institute for Contemporary Art, Berlin. Permanent collections include: The Metropolitan Museum of Art, New York; Tate Modern, London; Whitney Museum of American Art, New York; Centre Pompidou, Paris; Museum Fur Moderne Kunst, Frankfurt; and the Museum of Contemporary Art, Los Angeles. She is a graduate of Brown University and a Guggenheim Fellow. Simon has been a visiting artist at Yale University, Bard College, Harvard University and Columbia University. Her photography and writing have been featured in numerous publications and broadcasts including The New York Times Magazine, The New Yorker, Ted.com, CNN, BBC and Frontline. Steidl recently published An American Index of the Hidden and Unfamiliar. She is represented by Gagosian Gallery.

Source: Gagosian

White Tiger (Kenny), Selective Inbreeding
Turpentine Creek Wildlife Refuge and Foundation
Eureka Springs, Arkansas

In the United States, all living white tigers are the result of selective inbreeding to artificially create the genetic conditions that lead to white fur, ice-blue eyes and a pink nose. Kenny was born to a breeder in Bentonville, Arkansas on February 3, 1999. As a result of inbreeding, Kenny is mentally retarded and has significant physical limitations. Due to his deep-set nose, he has difficulty breathing and closing his jaw, his teeth are severely malformed and he limps from abnormal bone structure in his forearms. The three other tigers in Kenny’s litter are not considered to be quality white tigers as they are yellow coated, cross-eyed, and knock-kneed.

Avian Quarantine Facility
The New York Animal Import Center
Newburgh, New York

European Finches seized upon illegal importation into the U.S. and African Gray Parrots in quarantine.

All imported birds that are not of U.S. or Canadian origin must undergo a 30 day quarantine in a U.S. Department of Agriculture animal import quarantine facility. The quarantine is mandatory and at the owner’s expense. Birds are immediately placed in incubators called isolettes that control the spread of disease and prevent cross-contamination by strategically placed High Efficiency Particulate Air Filters.Before each quarantined bird is cleared for release, it is tested for Avian Influenza and Exotic Newcastle Disease.

U.S. Customs and Border Protection, Contraband Room
John F. Kennedy International Airport
Queens, New York

African cane rats infested with maggots, African yams (dioscorea), Andean potatoes, Bangladeshi cucurbit plants, bush meat, cherimoya fruit, curry leaves (murraya), dried orange peels, fresh eggs, giant African snail, impala skull cap, jackfruit seeds, June plum, kola nuts, mango, okra, passion fruit, pig nose, pig mouths, pork, raw poultry (chicken), South American pig head, South American tree tomatoes, South Asian lime infected with citrus canker, sugar cane (poaceae), uncooked meats, unidentified sub tropical plant in soil.

All items in the photograph were seized from the baggage of passengers arriving in the U.S. at JFK Terminal 4 from abroad over a 48-hour period. All seized items are identified, dissected, and then either ground up or incinerated. JFK processes more international passengers than any other airport in the United States.

Research Marijuana Crop Grow Room
National Center for Natural Products Research
Oxford, Mississippi

The National Center for Natural Products Research (NCNPR) is the only facility in the United States which is federally licensed to cultivate cannabis for scientific research. In addition to cultivating cannabis, NCNPR is responsible for analyzing seized marijuana for potency trends, herbicide residuals (paraquat) and fingerprint identification. NCNPR is licensed by the National Institute on Drug Abuse and also researches and develops chemicals derived from plants, marine organisms, and other natural products.

While 11 states have legalized the medical use of marijuana, a 2005 U.S. Supreme Court decision allows for the arrest of any individual caught using it for this purpose. Nearly half of the annual arrests for drug violations involve marijuana possession or trafficking.

Cryopreservation Unit
Cryonics Institute
Clinton Township, Michigan

This cryopreservation unit holds the bodies of Rhea and Elaine Ettinger, the mother and first wife of cryonics pioneer, Robert Ettinger. Robert, author of “The Prospect of Immortality” and “Man into Superman” is still alive.

The Cryonics Institute offers cryostasis (freezing) services for individuals and pets upon death. Cryostasis is practiced with the hope that lives will ultimately be extended through future developments in science, technology, and medicine. When, and if, these developments occur, Institute members hope to awake to an extended life in good health, free from disease or the aging process. Cryostasis must begin immediately upon legal death. A person or pet is infused with ice-preventive substances and quickly cooled to a temperature where physical decay virtually stops. The Cryonics Institute charges $28,000 for cryostasis if it is planned well in advance of legal death and $35,000 on shorter notice.

All images and text from Taryn Simon.
Buy the book here.
See her work here.

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“To research my new book, Elephants on Acid, I scoured scientific archives searching for the most bizarre experiments of all time — the kind that are mind-twistingly, jaw-droppingly strange… the kind that make you wonder, “How did anyone ever conceive of doing such a thing?”

Listed below are twenty of these experiments. You’ll find all of them (and about 80 more) discussed in greater detail in my book, which will be published November, 2007 by Harcourt. Kirkus Reviews calls it, “One of the finest science/history bathroom books of all time.”

There’s much more in the book than what’s posted here.
You can BUY IT NOW from Amazon.

#1: Elephants on Acid
What happens if you give an elephant LSD? On Friday August 3, 1962, a group of Oklahoma City researchers decided to find out.

Warren Thomas, Director of the City Zoo, fired a cartridge-syringe containing 297 milligrams of LSD into Tusko the Elephant’s rump. With Thomas were two scientific colleagues from the University of Oklahoma School of Medicine, Louis Jolyon West and Chester M. Pierce.

297 milligrams is a lot of LSD — about 3000 times the level of a typical human dose. In fact, it remains the largest dose of LSD ever given to a living creature. The researchers figured that, if they were going to give an elephant LSD, they better not give him too little.

Thomas, West, and Pierce later explained that the experiment was designed to find out if LSD would induce musth in an elephant — musth being a kind of temporary madness male elephants sometimes experience during which they become highly aggressive and secrete a sticky fluid from their temporal glands. But one suspects a small element of ghoulish curiosity might also have been involved.

Whatever the reason for the experiment, it almost immediately went awry. Tusko reacted to the shot as if a bee had stung him. He trumpeted around his pen for a few minutes, and then keeled over on his side. Horrified, the researchers tried to revive him, but about an hour later he was dead. The three scientists sheepishly concluded that, “It appears that the elephant is highly sensitive to the effects of LSD.”

In the years that followed controversy lingered over whether it was the LSD that killed Tusko, or the drugs used to revive him. So twenty years later, Ronald Siegel of UCLA decided to settle the debate by giving two elephants a dose similar to what Tusko received. Reportedly he had to sign an agreement promising to replace the animals in the event of their deaths.

Instead of injecting the elephants with LSD, Siegel mixed the drug into their water, and when it was administered in this way, the elephants not only survived but didn’t seem too upset at all. They acted sluggish, rocked back and forth, and made some strange vocalizations such as chirping and squeaking, but within a few hours they were back to normal. However, Siegel noted that the dosage Tusko received may have exceeded some threshold of toxicity, so he couldn’t rule out that LSD was the cause of his death. The controversy continues.
Comments (65)

#2: Obedience
Imagine that you’ve volunteered for an experiment, but when you show up at the lab you discover the researcher wants you to murder an innocent person. You protest, but the researcher firmly states, “The experiment requires that you do it.” Would you acquiesce and kill the person?

When asked what they would do in such a situation, almost everyone replies that of course they would refuse to commit murder. But Stanley Milgram’s famous obedience experiment, conducted at Yale University in the early 1960s, revealed that this optimistic belief is wrong. If the request is presented in the right way, almost all of us quite obediently become killers.

Milgram told subjects they were participating in an experiment to determine the effect of punishment on learning. One volunteer (who was, in reality, an actor in cahoots with Milgram) would attempt to memorize a series of word pairs. The other volunteer (the real subject) would read out the word pairs and give the learner an electric shock every time he got an answer wrong. The shocks would increase in intensity by fifteen volts with each wrong answer.

The experiment began. The learner started getting some wrong answers, and pretty soon the shocks had reached 120 volts. At this point the learner started crying out, “Hey, this really hurts.” At 150 volts the learner screamed in pain and demanded to be let out. Confused, the volunteers turned around and asked the researcher what they should do. He always calmly replied, “The experiment requires that you continue.”

Milgram had no interest in the effect of punishment on learning. What he really wanted to see was how long people would keep pressing the shock button before they refused to participate any further. Would they remain obedient to the authority of the researcher up to the point of killing someone?

To Milgram’s surprise, even though volunteers could plainly hear the agonized cries of the learner echoing through the walls of the lab from the neighboring room, two-thirds of them continued to press the shock button all the way up to the end of scale, 450 volts, by which time the learner had fallen into an eerie silence, apparently dead. Milgram’s subjects sweated and shook, and some laughed hysterically, but they kept pressing the button. Even more disturbingly, when volunteers could neither see nor hear feedback from the learner, compliance with the order to give ever greater shocks was almost 100%.

Milgram later commented, “I would say, on the basis of having observed a thousand people in the experiment and having my own intuition shaped and informed by these experiments, that if a system of death camps were set up in the United States of the sort we had seen in Nazi Germany, one would be able to find sufficient personnel for those camps in any medium-sized American town.”

[On YouTube: See scenes from Milgram's obedience experiment.]
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#3: Demikhov’s Two-Headed Dogs
In 1954 Vladimir Demikhov shocked the world by unveiling a surgically created monstrosity: A two-headed dog. He created the creature in a lab on the outskirts of Moscow by grafting the head, shoulders, and front legs of a puppy onto the neck of a mature German shepherd.

Demikhov paraded the dog before reporters from around the world. Journalists gasped as both heads simultaneously lapped at bowls of milk, and then cringed as the milk from the puppy’s head dribbled out the unconnected stump of its esophageal tube. The Soviet Union proudly boasted that the dog was proof of their nation’s medical preeminence.

Over the course of the next fifteen years, Demikhov created a total of twenty of his two-headed dogs. None of them lived very long, as they inevitably succumbed to problems of tissue rejection. The record was a month.

Demikhov explained that the dogs were part of a continuing series of experiments in surgical techniques, with his ultimate goal being to learn how to perform a human heart and lung transplant. Another surgeon beat him to this goal — Dr. Christian Baarnard in 1967 — but Demikhov is widely credited with paving the way for it.

[On YouTube: See a Russian-language film about Demikhov.]
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#4: The Initiation of Heterosexual Behavior in a Homosexual Male
In 1954 James Olds and Peter Milner of McGill University discovered that the septal region is the feel-good center of the brain. Electrical stimulation of it produces sensations of intense pleasure and sexual arousal. They demonstrated their discovery by inserting wires into a rat’s brain and then showing that when the rat figured out it could self-stimulate itself by pressing a lever, it would maniacally bang on that lever up to two-thousand times an hour. (The image at the very top of this page, third from the right, shows one of Olds and Milner’s rats banging on its lever.)

In 1970, Robert Heath of Tulane University dreamed up a far more novel application of Olds and Milner’s discovery. Heath decided to test whether repeated stimulation of the septal region could transform a homosexual man into a heterosexual.

Heath referred to his homosexual subject as patient B-19. He inserted Teflon-insulated electrodes into the septal region of B-19′s brain and then gave B-19 carefully controlled amounts of stimulation in experimental sessions. Soon the young man was reporting increased stirrings of sexual motivation. Heath then rigged up a device to allow B-19 to self-stimulate himself. It was like letting a chocoholic loose in a candy shop. B-19 quickly became obsessed with the pleasure button. In one three-hour session he pressed it 1500 times until, as Heath noted, “he was experiencing an almost overwhelming euphoria and elation and had to be disconnected.”

By this stage of the experiment B-19′s libido was so jacked up that Heath decided to proceed with the final stage in which B-19 would be introduced to a sexually-willing female partner. With permission from the state attorney general, Heath arranged for a twenty-one-year-old female prostitute to visit the lab, and he placed her in a room with B-19. For an hour B-19 did nothing, but then the prostitute took the initiative and a successful sexual encounter between the two occurred. Heath considered this a positive result.

Little is known of B-19′s later fate. Heath reported that the young man drifted back into a life of homosexual prostitution, but that he also had an affair with a married woman. Heath optimistically decided that this showed the treatment was at least partially successful. However, Heath never did try to convert any more homosexuals.
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#5: The Isolated Head of a Dog
What could be more horrific than creating a two-headed dog? What about keeping the severed head of a dog alive apart from its body!

Ever since the carnage of the French Revolution, when the guillotine sent thousands of severed heads tumbling into baskets, scientists had wondered whether it would be possible to keep a head alive apart from its body, but it wasn’t until the late 1920s that someone managed to pull off this feat.

Soviet physician Sergei Brukhonenko developed a primitive heart-lung machine he called an “autojector,” and with this device he succeeded in keeping the severed head of a dog alive. He displayed one of his living dog heads in 1928 before an international audience of scientists at the Third Congress of Physiologists of the USSR. To prove that the head lying on the table really was alive, he showed that it reacted to stimuli. Brukhonenko banged a hammer on the table, and the head flinched. He shone light in its eyes, and the eyes blinked. He even fed the head a piece of cheese, which promptly popped out the esophageal tube on the other end.

Brukhonenko’s severed dog head became the talk of Europe and inspired the playwright George Bernard Shaw to muse, “I am even tempted to have my own head cut off so that I can continue to dictate plays and books without being bothered by illness, without having to dress and undress, without having to eat, without having anything else to do other than to produce masterpieces of dramatic art and literature.”

[On YouTube: See Experiments in the revival of organisms.]
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#6: Human-Ape Hybrid
For decades dark rumors circulated alleging that the Soviets had conducted experiments to try to create a human-ape hybrid by breeding chimpanzees and humans, but it wasn’t until the collapse of the Soviet Union and the opening of Russian archives that the rumors were confirmed.

Dr. Il’ya Ivanov was a world-renowned expert on veterinary reproductive biology, but he wanted to do more in life than breed fatter cows. So in 1927 he traveled to Africa to pursue his vision of interbreeding man and ape.

Thankfully his efforts weren’t successful. To a great degree this was due to the native staff of the West Guinea research facility where he worked, from whom he constantly had to conceal the true purpose of his experiments. If they had found out what he was really doing, he wrote in his diary, “this could have led to very unpleasant consequences.” The necessity of carrying out his work in secrecy made it almost impossible to do anything, although he did record two unsuccessful attempts to artificially inseminate female chimpanzees with human sperm.

Frustrated, Ivanov eventually returned to the Soviet Union. He brought an orangutan named Tarzan back with him, hoping to continue his research in a more accepting environment. Back home he advertised for female volunteers willing to carry Tarzan’s child, and remarkably he got a few takers. But then Tarzan died and Ivanov himself was sent off to a prison camp for a couple of years. This ended his research. There are vague rumors suggesting that other Soviet scientists continued Ivanov’s work, but nothing definite has been proven.
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#7: The Stanford Prison Experiment
Philip Zimbardo was curious about why prisons are such violent places. Is it because of the character of their inhabitants, or is it due to the corrosive effect of the power structure of the prisons themselves?

To find out, Zimbardo created a mock prison in the basement of the Stanford psychology department. He recruited clean-cut young men as volunteers — none had criminal records and all rated “normal” on psychological tests — and he randomly assigned half of them to play the role of prisoners and the other half to play guards. His plan was that he would step back for two weeks and observe how these model citizens interacted with each other in their new roles.

What happened next has become the stuff of legend.

Social conditions in the mock prison deteriorated with stunning rapidity. On the first night the prisoners staged a revolt, and the guards, feeling threatened by the insubordination of the prisoners, cracked down hard. They began devising creative ways to discipline the prisoners, using methods such as random strip-searches, curtailed bathroom privileges, verbal abuse, sleep deprivation, and the withholding of food.

Under this pressure, prisoners began to crack. The first one left after only thirty-six hours, screaming that he felt like he was “burning up inside.” Within six days, four more prisoners had followed his lead, one of whom had broken out in a full-body stress-related rash. It was clear that for everyone involved the new roles had quickly become more than just a game.

Even Zimbardo himself felt seduced by the corrosive psychology of the situation. He began entertaining paranoid fears that his prisoners were planning a break-out, and he tried to contact the real police for help. Luckily, at this point Zimbardo realized things had gone too far. Only six days had passed, but already the happy college kids who had begun the experiment had transformed into sullen prisoners and sadistic guards.

Zimbardo called a meeting the next morning and told everyone they could go home. The remaining prisoners were relieved, but tellingly, the guards were upset. They had been quite enjoying their new-found power and had no desire to give it up.
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#8: Facial expressions while decapitating a rat
In 1924 Carney Landis, a graduate student in psychology at the University of Minnesota, designed an experiment to study whether emotions evoke characteristic facial expressions. For instance, is there one expression everyone uses to convey shock, and another commonly used to display disgust?

Most of Landis’s subjects were fellow graduate students. He brought them into his lab and painted lines on their faces so that he could more easily see the movement of their muscles. He then exposed them to a variety of stimuli designed to provoke a strong psychological reaction. As they reacted, he snapped pictures of their faces. He made them smell ammonia, look at pornographic pictures, and reach their hand into a bucket containing slimy frogs. But the climax of the experiment arrived when he carried out a live white rat on a tray and asked them to decapitate it.

Most people initially resisted his request, but eventually two-thirds did as he ordered. Landis noted that most of them performed the task quite clumsily: “The effort and attempt to hurry usually resulted in a rather awkward and prolonged job of decapitation.” For the one-third that refused, Landis eventually picked up the knife and decapitated the rat for them.

Landis’s experiment presented a stunning display of the willingness of people to obey the demands of experimenters, no matter how bizarre those demands might be. It anticipated the results of Milgram’s obedience experiment by almost forty years. However, Landis never realized that the compliance of his subjects was far more interesting than their facial expressions. Landis remained single-mindedly focused on his initial research topic, even though he never was able to match up emotions and expressions. It turns out that people use a wide variety of expressions to convey the same emotion — even an emotion such as disgust at having to decapitate a rat.
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#9: The Vomit-Drinking Doctor
How far would you go to prove a theory? Stubbins Ffirth, a doctor-in-training living in Philadelphia during the early nineteenth century, went further than most. Way further.

Having observed that yellow fever ran riot during the summer, but disappeared during the winter, Ffirth concluded that it was not a contagious disease. Instead, he theorized it was caused by an excess of stimulants such as heat, food, and noise.

To prove his theory, Ffirth set out to demonstrate that no matter how much he exposed himself to yellow fever, he wouldn’t catch it. He started by making small incisions on his arms and pouring “fresh black vomit” obtained from a yellow-fever patient into the cuts. He didn’t get sick.

Next he dribbled some vomit in his eyes. He fried some up on a skillet and inhaled the fumes. He fashioned some into a pill and swallowed it. Finally he took to drinking entire glasses of pure, undiluted black vomit. And still he didn’t get sick.

Ffirth rounded out his experiment by liberally smearing himself with other yellow-fever tainted fluids: blood, saliva, perspiration, and urine. Healthy as ever, he declared his theory proven. Unfortunately, he was wrong. Yellow fever is very contagious, but it requires direct transmission into the blood stream, usually by a mosquito, to cause infection. But considering all Ffirth did to infect himself, it is a bit of a miracle he remained alive.
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#10: Beneficial Brainwashing
Dr. Ewen Cameron believed he had come up with a cure for schizophrenia. His theory was that the brain could be reprogrammed to think in healthy ways by forcibly imposing new thought patterns on it. His method was to make patients wear headphones and listen to audio messages looped over and over, sometimes for days or even weeks at a time. He called this method “psychic driving,” because the messages were being driven into the psyche. The press hailed it as “beneficial brainwashing.”

During the 1950s and early 1960s, hundreds of Cameron’s patients at Montreal’s Allan Memorial Clinic became his unwitting test subjects — whether or not they actually had schizophrenia. Some patients checked in complaining of problems as minor as menopause-related anxiety, only to find themselves sedated with barbiturates, strapped into a bed, and forced to listen for days on end to messages such as “People like you and need you. You have confidence in yourself.”

One time, to test the technique, Cameron placed patients into a drugged sleep and made them listen to the message, “When you see a piece of paper, you want to pick it up.” Later he drove them to a local gymnasium. There, lying in the middle of the gym floor, was a single piece of paper. He happily reported that many of them spontaneously walked over to pick it up.

When the CIA learned of what Cameron was doing, it became interested and started surreptitiously channeling him money. But eventually the agency concluded that Cameron’s technique was a failure and cut his funding, prompting Cameron himself to admit that his experiments had been “a ten year trip down the wrong road.” In the late 1970s a group of Cameron’s former patients filed suit against the CIA for its support of his work and reached an out-of-court settlement for an undisclosed amount of money.

#11: Monkey-Head Transplant
When Vladimir Demikhov unveiled his two-headed dogs in 1954, it inspired a strange kind of surgical arms race (or rather, head race) between the two superpowers. Eager to prove that its surgeons were actually the best in the world, the American government began funding the work of Robert White, who then embarked on a series of experimental surgeries, performed at his brain research center in Cleveland, Ohio, resulting in the world’s first successful monkey-head transplant.

The head transplant occurred on March 14, 1970. It took White and his assistants hours to perform the carefully choreographed operation, separating a monkey’s head from its body and reattaching it to a new body. When the monkey woke and found that its body had been switched for a new one, it angrily tracked White with its eyes and snapped at him with its teeth. The monkey survived a day and a half before succumbing to complications from the surgery. As bad as it was for the monkey, it could have been worse. White noted that, from a surgical point of view, it would have been easier to put the monkey’s head on backwards.

White thought he should have been treated like a hero, but instead the public was appalled by what he had done. Nevertheless, White soldiered on, campaigning to raise support for a human head transplant. He toured with Craig Vetovitz, a near-quadriplegic, who volunteered to be the first to undergo the procedure. The public is still a long way from accepting the idea of human head transplants, but if White has his way, one day it will happen.
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#12: The Remote-Controlled Bull
Yale researcher Jose Delgado stood in the hot sun of a bullring in Cordova, Spain. With him in the ring was a large, angry bull. The animal noticed him and began to charge. It gathered speed. Delgado appeared defenseless, but when the bull was mere feet away, Delgado pressed a button on a remote control unit in his hand, sending a signal to a chip implanted in the bull’s brain. Abruptly, the animal stopped in its tracks. It huffed and puffed a few times, and then walked docilely away.

Delgado’s experience in the ring was an experimental demonstration of the ability of his “stimoceiver” to manipulate behavior. The stimoceiver was a computer chip, operated by a remote-control unit, that could be used to electrically stimulate different regions of an animal’s brain. Such stimulation could produce a wide variety of effects, including the involuntary movement of limbs, the eliciting of emotions such as love or rage, or the inhibition of appetite. It could also be used, as Delgado showed, to stop a charging bull.

Delgado’s experiment sounds so much like science fiction, that many people are surprised to learn it occurred back in 1963. During the 1970s and 80s, research into electrical stimulation of the brain (ESB) languished, stigmatized by the perception that it represented an effort to control people’s minds and thoughts. But more recently, ESB research has once again been flourishing, with reports of researchers creating remote-controlled rats, pigeons, and even sharks.
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#13: The Ape and the Child
History contains numerous accounts of children raised by animals. The children in such cases often continue to act more animal than human, even when returned to human society. The psychologist Winthrop Kellogg wondered what would happen if the situation were reversed. What if an animal were raised by humans — as a human. Would it eventually act like a human?

To answer this question, in 1931 Kellogg brought a seven-month-old female chimpanzee named Gua into his home. He and his wife then proceeded to raise her as if she were human, treating her exactly the same as they treated their ten-month-old son Donald.

Donald and Gua played together. They were fed together. And the Kelloggs subjected them both to regular tests to track their development. One such test was the suspended cookie test, in which the Kelloggs timed how long it took their children to reach a cookie suspended by a string in the middle of the room.

Gua regularly performed better on such tests than Donald, but in terms of language acquisition she was a disappointment. Despite the Kelloggs’s repeated efforts, the ability to speak eluded her. Disturbingly, it also seemed to be eluding Donald. Nine months into the experiment, his language skills weren’t much better than Gua’s. When he one day indicated he was hungry by imitating Gua’s “food bark,” the Kelloggs decided the experiment had gone far enough. Donald evidently needed some playmates of his own species. So on March 28, 1932 they shipped Gua back to the primate center. She was never heard from again.
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#14: “My Fingernails Taste Terribly Bitter”
In the summer of 1942 Professor Lawrence Leshan stood in the darkness of a cabin in an upstate New York camp where a row of young boys lay sleeping. He spoke aloud, repeating a single phrase over and over, “My fingernails taste terribly bitter. My fingernails taste terribly bitter.”

Nowadays that kind of behavior could get one locked away, but Leshan wasn’t mad. He was conducting a sleep-learning experiment. All the boys had been diagnosed as chronic nail-biters, and Leshan wanted to find out if nocturnal exposure to a negative suggestion about nail biting would cure them of their bad habit.

Leshan initially used a phonograph to play the message. It faithfully repeated the phrase 300 times a night as the boys lay sleeping. But five weeks into the experiment, the phonograph broke. Leshan improvised by standing in the darkness and speaking the message himself.

At the end of the summer, Leshan examined the boys’ nails and concluded that 40% of them had kicked the habit. The sleep-learning effect seemed to be real. However, other researchers later disputed this conclusion. In a 1956 experiment at Santa Monica College, William Emmons and Charles Simon used an electroencephalograph to make sure subjects were fully asleep before playing a message. Under these conditions, the sleep-learning effect disappeared.
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#15: The Electrification of Human Corpses
In 1780 the Italian anatomy professor Luigi Galvani discovered that a spark of electricity could cause the limbs of a dead frog to twitch. Soon men of science throughout Europe were repeating his experiment, but it didn’t take them long to bore of frogs and turn their attention to more interesting animals. What would happen, they wondered, if you electrified a human corpse?

Galvani’s nephew, Giovanni Aldini, embarked on a tour of Europe in which he offered audiences the chance to see this stomach-turning spectacle. His most celebrated demonstration occurred on January 17, 1803 when he applied the poles of a 120-volt battery to the body of the executed murderer George Forster.

When Aldini placed wires on the mouth and ear, the jaw muscles quivered and the murderer’s features twisted in a rictus of pain. The left eye opened as if to gaze upon his torturer. For the grand finale Aldini hooked one wire to the ear and plunged the other up the rectum. Forster’s corpse broke into a hideous dance. The London Times wrote, “It appeared to the uninformed part of the bystanders as if the wretched man was on the eve of being restored to life.”

Other researchers tried electrifying bodies, with the specific hope of restoring them to life, but with no success. Early nineteenth-century experiments of this kind are considered to have been one of Mary Shelley’s main sources of inspiration when she wrote her novel Frankenstein in 1816.
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#16: Seeing Through Cat’s Eyes
In 1999 researchers led by Dr. Yang Dan, an assistant professor of neurobiology at the University of California, Berkeley, anesthetized a cat with sodium pentothal, chemically paralyzed it with Norcuron, and secured it tightly in a surgical frame. They then glued metal posts to the whites of its eyes, and forced it to look a screen that showed scene after scene of swaying trees and turtleneck-wearing men.

This was not a form of Clockword-Orange-style aversion therapy for cats. Instead, it was a remarkable attempt to tap into another creature’s brain and see directly through its eyes. The researchers had inserted fiber electrodes into the vision-processing center of the cat’s brain. The electrodes measured the electrical activity of the brain cells and transmitted this information to a nearby computer which decoded the information and transformed it into a visual image. As the cat watched the images of the trees and the turtleneck-wearing guy, the same images emerged (slightly blurrier) on the computer screen across the room.

The commercial potential of the technology is mind-boggling. Forget helmet-cam at the superbowl; get ready for eye-cam. Or how about this — never carry a camera again. Take pictures by blinking your eyes. It would work great unless you had a few too many drinks on vacation.
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#17: Stimuli Eliciting Sexual Behavior in Turkeys
Male turkeys aren’t fussy. Give them a lifelike model of a female turkey and they’ll happily try to mate with it as eagerly as they would with the real thing.

This observation intrigued Martin Schein and Edgar Hale of the University of Pennsylvania, and made them curious about what might be the minimal stimulus required to excite a turkey. They embarked on a series of experiments to find out. This involved removing parts from the turkey model one by one, until the male turkey eventually lost interest.

Tail, feet, and wings were all removed, but still the clueless bird waddled up to the model, let out an amorous gobble, and tried to do his thing. Finally, the researchers were left with a head on a stick. And surprisingly, the male turkey still showed great interest. In fact, it preferred a head on a stick over a headless body.

Schein and Hale subsequently investigated how minimal they could make the head itself before it failed to elicit a response. They discovered that freshly severed female heads impaled on sticks worked best, but if the male turkey had nothing else it would settle for a plain balsa wood head. Turkeys evidently adhere to the philosophy that if you can’t be with the one you love, then love the one you’re with.

Curious about the mating habits of other poultry, Schein and Hale performed similar tests on White Leghorn Cocks. For those curious, they published their results in an article that boasts one of the most evocative titles in all of science: “Effects of morphological variations of chicken models on sexual responses of cocks.”
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#18: “Would You Go To Bed With Me Tonight?”
If you were a man walking across the campus of Florida State University in 1978, an attractive young woman might have approached you and said these exact words: “I have been noticing you around campus. I find you to be attractive. Would you go to bed with me tonight?”

If you were that man, you probably would have thought that you had just gotten incredibly lucky. But not really. You were actually an unwitting subject in an experiment designed by the psychologist Russell Clark.

Clark had persuaded the students of his social psychology class to help him find out which gender, in a real-life situation, would be more receptive to a sexual offer from a stranger. The only way to find out, he figured, was to actually get out there and see what would happen. So young men and women from his class fanned out across campus and began propositioning strangers.

The results weren’t very surprising. Seventy-five percent of guys were happy to oblige an attractive female stranger (and those who said no typically offered an excuse such as, “I’m married”). But not a single woman accepted the identical offer of an attractive male. In fact, most of them demanded the guy leave her alone.

At first the psychological community dismissed Clark’s experiment as a trivial stunt, but gradually his experiment gained first acceptance, and then praise for how dramatically it revealed the differing sexual attitudes of men and women. Today it’s considered a classic. But why men and women display such different attitudes remains as hotly debated as ever.
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#19: Shock the Puppy
When Stanley Milgram published the results of his obedience experiment in 1963, it sent shockwaves through the scientific community. Other researchers found it hard to believe that people could be so easily manipulated, and they searched for any mistakes Milgram might have made. Charles Sheridan and Richard King theorized that perhaps Milgram’s subjects had merely played along with the experiment because they realized the victim was faking his cries of pain. To test this possibility, Sheridan and King decided to repeat Milgram’s experiment, introducing one significant difference. Instead of using an actor, they would use an actual victim who would really get shocked. Obviously they couldn’t use a human for this purpose, so they used the next best thing — a cute, fluffy puppy.

Sheridan and King told their subjects — volunteers from an undergraduate psychology course — that the puppy was being trained to distinguish between a flickering and a steady light. It had to stand either to the right or the left depending on the cue from the light. If the animal failed to stand in the correct place, the subjects had to press a switch to shock it. As in the Milgram experiment, the shock level increased 15 volts for every wrong answer. But unlike the Milgram experiment, the puppy really was getting zapped.

As the voltage increased, the puppy first barked, then jumped up and down, and finally started howling with pain. The volunteers were horrified. They paced back and forth, hyperventilated, and gestured with their hands to show the puppy where to stand. Many openly wept. Yet the majority of them, twenty out of twenty-six, kept pushing the shock button right up to the maximum voltage.

Intriguingly, the six students who refused to go on were all men. All thirteen women who participated in the experiment obeyed right up until the end.
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#20: Heartbeat At Death
On October 31, 1938, John Deering took a last drag on his cigarette, sat down in a chair, and allowed a prison guard to place a black hood over his head and pin a target to his chest. Next the guard attached electronic sensors to Deering’s wrists.

Deering had volunteered to participate in an experiment, the first of its kind, to have his heartbeat recorded as he was shot through the chest by a firing squad. The prison physician, Dr. Stephen Besley, figured that since Deering was being executed anyway, science might as well benefit from the event. Perhaps some valuable information about the effect of fear on the heart could be learned.

The electrocardiogram immediately disclosed that, despite Deering’s calm exterior, his heart was beating like a jackhammer at 120 beats per minute. The sheriff gave the order to fire, and Deering’s heartbeat raced up to 180 beats per minute. Then four bullets ripped into his chest, knocking him back in his chair. One bullet bore directly into the right side of his heart. For four seconds his heart spasmed. A moment later it spasmed again. Then the rhythm gradually declined until, 15.4 seconds after the first shot, Deering’s heart stopped.

The next day Dr. Besley offered the press a eulogy of sorts for Deering: “He put on a good front. The electrocardiograph film shows his bold demeanor hid the actual emotions pounding within him. He was scared to death.”

Source museum of hoaxes.

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Genetically Engineered Sound Garden.

The debate around Genetic Engineering is currently centered around vital issues such as food, healthcare and the environment. However, we have been shaping nature for thousands of years, not only to suit our needs, but our most irrational desires. Beautiful flowers, mind altering weeds and crabs shaped like human faces all thrive on these desires, giving them an evolutionary advantage. By presenting a fantastical acoustic garden, a controlled ecosystem of entertainment, I aim to explore our cultural and aesthetic relationship to nature, and to question its future in the age of Synthetic Biology.

Scientific Advisors:
– Christina Agapakis, PhD Candidate, Biological and Biomedical Sciences, Harvard University. Oscillator
– Kirsten Jensen, Research Associate and James Chapell, PhD Candidate,Macromolecular Structure and Function Research Group, Division of Molecular Biosciences, Imperial College London

Thanks to:
Tommaso LanzaTim OldenEmily Hayes, James Brown and PJ Steiner at the Haseloff Lab, Cambridge

Singing flower. Because the parasite diverts the plant’s energy for its own purposes, only small flowers manage to grow.

Modified Agrobacterium takes sugars and nutrients from the host plant to encourage the growth of parasitic galls and fill them with gas to produce sound.

Lab Testing Rig: Factors like tension and temperature are modulated to fine tune the sound.

Lab Experiment from David Benqué on Vimeo.


String-Nut and bugs engineered to chew in rhythm.

Desired traits such as volume, timbre and harmony are acquired through selective breeding techniques.

Grafting, an age old practice (since at least 2000 BC.), is used to create harmonic notes combinations on a single tree.

Silvery Acres from David Benqué on Vimeo.

All text and images from David Benque.

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